Biotin metabolic absorption and physiological function

Biotin, moreover called vitamin H, coenzyme R. Biotin is a ureido globe containing a sulfur mark and one stinging gang chain, Wholesale Jewelry, are known to retain 8 isomers, absolutely modern only alpha-biotin, and hold biological activity

Biotin metabolic absorption and physiological function

Biotin is colorless acicular crystal, Wholesale Silver Jewelry, easy to soluble in water,slightly soluble in cold water, soluble in ethanol, solid in organicsolvents With wellbeing thermal stability, standard cooking loss is not big, strongacid, strong alkali and oxidant can axe it, ultraviolet glimmer also can makeit gradual destruction. Biotin principally stored in the liver, contain diminish levelsin blood

Metabolic absorption: biotin in food is mostlyexist in unshackle den or combined with proteins Biotin binding with protein in therole of intestinal protease, Jewelry manufacturer, tunnel biocytin, then through the locomotion of intestinalbiotin enzyme, discharge discharge biotin. The main parts of biotin absorption isproximal trivial bowel The low concentration is active engrossed by carriertransport; the colossal concentration is engrossed by simple diffusion burrow Theabsorption biotin via portal circulation, transported to the liver, kidneyinternal storage, buy wholesale Jewelry, fresh cells furthermore contain biotin, but less. Human intestinalbacteria can from two Pimelic sharp instead of azelaic acid to synthetizebiotin, but as the biotin direct source is not enough The biotin in human bodyis principally by the urinary excretion, milk besides has a biotin discharge, but thequantity is thumping few

Physiological function: the highest functionof biotin is playing a role in decarboxylation, buy wholesale Silver Jewelry, coenzyme function carboxylationreaction and hydrogenation reaction, can transferred CO2 from one alloy toanother compound, so that a alloy turn into another. Pharmacological dosesof biotin can decrease type I diabetes blood sugar levels, refine theexperimental rats glucose tolerance, insulin resistance Biotin further canmaintain various empirical animals unaffected cells to natural function

Normal need: because of the gut bacteria cansynthesize biotin, so it is not feasible to accurately determine the biotinrequirement Adult daily intake is 30 micrograms, baby promote daily intake is 35micrograms; Excessive reaction: the biotin toxicity is extremely low, so far thereis no biotin toxicity report

Deficiency: researches by cosmeticraw allied suppliers found that biotin need is chiefly appear skinsymptoms, such as perceptible hair thinning, loss of luster, scrape dry, scalydermatitis, red rash, dire scab can limit around the eyes, nose andmouth In addition, accompanied by loss of appetite, nausea, vomiting, mucosalatrophy of tongue papillae, mucosa grey, numbness, depression, fatigue,myalgia, hypercholesterolemia and divergent electroencephalogram. These symptomsoccur in biotin scarcity after 10 weeks Babies below 6 months of age canappear seborrheic dermatitis

From biotinsupplier we recognize biotin widely exists in fare cheese, liver, kidney,cheese, soy, wheat, rice, strawberry, grape, grapefruit, beer, liver, eggs,lean meat, dairy products. People like to eat uncooked eggs and drinking wine and coffeeneed to add biotin; antibiotics or sulfa daily intake of at least 25 g; menwith thinning hair intake of biotin, discourage hair loss produce is obvious; inpregnancy, biotin leave loss quickly, should complement impartial below theguidance of the physician

Source:http://wwwcosprm.com

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